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Emily Owens finds out that life in a hospital isn't very different from life in high school on the premiere of Emily Owens, M.D. On the first day of her residency, Emily finds that she'll be working alongside both her crush, Will Collins, and her arch-nemesis, Cassandra Kopelson.

Emily treats a 12 year old girl who convinces her to tell Will that she likes him and Emily assists on her first surgery despite being told by Dr. Gina Bindari that it will be years before she will see the inside of an OR which sets Emily apart from the other surgical residents.

She and Cassandra also treat a patient with Alzheimer's whose daughter has abandoned her at the hospital.

Dr. Micah Barnes, Chief Resident, has a secret.

Emily Owens, M.D.
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Emily Owens, M.D. Season 1 Episode 1 Quotes

Tyra: You've got your jocks, aka the orthopedic surgeons. Mean girls go into plastics. Your All-American, girl next door types, they're gonna be in OB. The true geeks, they're the neurologists. The rebels are in the ER. Stoners, anesthesia, and peds gets your sanctimonious church-goers.
Emily: How about us.
Tyra: Surgery's a melting pot, a little bit of everything, which basically means none of us get along.

I wasn't one of those kids who thrived in high school. I was geeky. Alright, I was very geeky...high school was rough. But, you know what got me through? The knowledge that I'd outgrow all those feelings of insecurity and in