Katherine Heigl is Pregnant!

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Katherine in Bed
In a new movie, that is.

The Grey's Anatomy star is set to appear in Knocked Up, a Universal Pictures project and writer/director Judd Apatow's follow-up to his successful The 40-Year-Old Virgin. The film is scheduled for a 2007 release, and revolves around an unexpected pregnancy and other consequences of a one-night stand. Why anyone would leave Katherine after a one-night stand is perplexing, but that's just us.

Heigl, who stars as Dr. Isobel "Izzie" Stevens on Grey's Anatomy, takes over the role vacated by Anne Hathaway, star of The Princess Diaries and Brokeback Mountain. Hathaway withdrew from Knocked Up due to creative differences. Seth Rogan, Paul Rudd and Leslie Mann, all of whom starred in The 40-Year-Old Virgin, have been cast along with the 27-year old Heigl.

Katherine's most recent film was The Ringer, where she starred alongside Johnny Knoxville, as he tried to fix the Special Olympics. What a jackass!

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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contenting code tearful overprinting subproject?perusal affirming

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I love Grey's Anatomy!!It's the best show ever!!

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Grey's Anatomy is thee best show ever!!! I'm so glad meredith didn't die! It's GREY'S Anatomy! So if Meredith GREY died, they might've ended the show!!!!!!!!

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ecstatic even if she really is pregant ha ha especially since her singer/songwriter boyfriend is an amazing guy, they would make beautiful chldren- sorry off topic, I get excited over the 'pregnant' shout out want to say was I'm so happy for the news and that she's continue to work. I hope the strory will be a s good as the first.

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That's not funny to joke about! I thought we were gonna lose my girl!

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Grey's Anatomy Quotes

[narrating] "At some point, you have to make a decision. Boundaries don't keep other people out, they fence you in. Life is messy, that's how we're made. So you can waste your life drawing lines or you can live your life crossing them. But there are some lines that are way too dangerous to cross. Here's what I know. If you're willing to throw caution to the wind and take a chance, the view from the other side... is spectacular."

MEREDITH

Richard: Chin up. Put your shoulders back, walk proud, strut a little. Don't lick your wounds: celebrate them. The scars you bear are the signs of a competitor. You're in a lion fight, Stevens. Just because you didn't win doesn't mean you don't know how to roar.