Katherine Heigl is Pregnant!

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Katherine in Bed
In a new movie, that is.

The Grey's Anatomy star is set to appear in Knocked Up, a Universal Pictures project and writer/director Judd Apatow's follow-up to his successful The 40-Year-Old Virgin. The film is scheduled for a 2007 release, and revolves around an unexpected pregnancy and other consequences of a one-night stand. Why anyone would leave Katherine after a one-night stand is perplexing, but that's just us.

Heigl, who stars as Dr. Isobel "Izzie" Stevens on Grey's Anatomy, takes over the role vacated by Anne Hathaway, star of The Princess Diaries and Brokeback Mountain. Hathaway withdrew from Knocked Up due to creative differences. Seth Rogan, Paul Rudd and Leslie Mann, all of whom starred in The 40-Year-Old Virgin, have been cast along with the 27-year old Heigl.

Katherine's most recent film was The Ringer, where she starred alongside Johnny Knoxville, as he tried to fix the Special Olympics. What a jackass!

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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contenting code tearful overprinting subproject?perusal affirming

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I love Grey's Anatomy!!It's the best show ever!!

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Grey's Anatomy is thee best show ever!!! I'm so glad meredith didn't die! It's GREY'S Anatomy! So if Meredith GREY died, they might've ended the show!!!!!!!!

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ecstatic even if she really is pregant ha ha especially since her singer/songwriter boyfriend is an amazing guy, they would make beautiful chldren- sorry off topic, I get excited over the 'pregnant' shout out want to say was I'm so happy for the news and that she's continue to work. I hope the strory will be a s good as the first.

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That's not funny to joke about! I thought we were gonna lose my girl!

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

Derek: I wanna be with you forever, and you wanna be with me forever. In order to do that we need to make vows. A commitment. A contract. Give me a piece of paper.
Meredith: I don't! I... I... I don't. I have post its!
Derek: (takes the post its and a pen) Ok. What do we wanna promise each other?
Meredith: That you'll love me... even when you hate me.
Derek: To love each other, even when we hate each other. (writes it down) No running. Ever! (Mer smiles and comes and sits in front of him) Nobody walks out. No matter what happens.
Meredith: No running.
Derek: (writes it down) What else?
Meredith: That we'll take care of each other, even when we're old, and smelly, and senile. And... if I get Alzheimer's and forget you...
Derek: I will remind you who I am, every day. To take care when old, senile, and smelly (writes it down) This is forever. (signs it) Sign.
Meredith: This is our wedding. A post it? (smiles)
Derek: Mhmmm. If you sign it.
Meredith: (signs it, and hands it back. Has tears in her eyes) Now what?
Derek: Now I kiss the bride. (They kiss)
Meredith: (smiling) Married.
Derek: (smiling) Married. (sticks their post it in Mer's locker) You see that? (Mer nods and smiles) Plenty of time.