"The Heart of the Matter" Previews & Promos

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Below is a funny sneak preview of "The Heart of the Matter," the fourth episode of Season Four of Grey's Anatomy. Callie and Izzie are getting ready to throw down... and the meek George is caught in the middle. High noon at Seattle Grace!


Follow the jump for another sneak peak - an intense clip in which a head trauma patient's father becomes abusive and Derek tells Cristina she has to avoid that exact behavior herself and do better at the teaching facet of being a resident ...


Looks like a good one. Check out our episode main page for "The Heart of the Matter" for links to more previews and photos from Thursday's episode (our episode guide and quotes will also appear there after the show airs). You can also discuss it (and everything Grey's Anatomy) in our forum, as always!

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.


Callie is in charge of the place now. Why on earth she would fight with Izzie in the hospital? There is just no way. The question is, why Izzie think Callie is going ot fight with her? Don't know.
Anyway, I want Callie to win regardless. Callie has not done anything wrong. She loved George and has been nice to him all these time. It's Izzie who's driving George crazy. It's Greoge who makes rash decisions or changes his mind.
I think they should end the marriage. Callie should be with someone who has potential, not a loser like George who can't even graduate. As for Lexi, I like her. She's pretty, but I don't want her to take the spotlight from Meredith. I hope Lex would leave the show soon, or that they will not extend her contract. She has to go. Also, bring some new guys for the girls. Callie needs a new man in her life. Christina should get one also. As for Izzie, maybe she will have one also (not George though). Maybe they will bring someone for Meredity which would make the show interesting as I would love to see McDreamy and Meredith get together.


Ok, SERIOUSLY This is Grey's - not WWF Raw. Even in the clip you can see that Callie's looking at Izzie like she's whacked. It is pretty funny, but Callie is not going to get all street in the cafeteria of the hospital... My money would be on Callie if she did though.


i don't know why so many people are against Izzie, but i think that they are both equal in overall strength in many different ways. Physical is just a small part of strength. And, if they were to fight, i wouldn't want either of them to win/loose, rather reach a mutual consensus and sort out this issue once and for all..it's all up to geroge i say!


Callie never had any intention of fighting Izzie. She probably just wants to expose her. And if they were going to fight, Callie would win. Izzie's whole trailer park persona is not convincing. She may have used it to intimidate Christina once, but she wouldn't stand a chance against Callie. And if they did fight (which they will not), I would want Callie to beat Izzie up because I am tired of her self-righteous and selfish hypocrisy. She wants George when he put someone else before her, but she paid him no mind before and couldn't even believe that Callie would seriously be interested in him.


I'm sure that Callie don't wanna fight. She surely just want to talk...I hope not cause I would like to seem them fight!!


naaaaaaaaaaaah. callie and izzie wont fight, its just a wind-up. still, it would be fun to watch if they do.


I want to see Adele and the Chief post losing their baby. Callie and Izzie: who cares? It's not like they are really gonna fight in the workplace.


Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.