"Physical Attraction, Chemical Reaction" Guide & More

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Another episode of Grey's Anatomy means a lot of hookups, stories, twists and turns to catch up on. Relive it all in the Insider's official episode guide!

You can scroll down the page or follow the link to check out last night's Grey's Anatomy music selections, and our photo gallery is also live for your enjoyment. We are still in the process of pulling together our list of memorable quotes from the episode. They should be up throughout the day today and into tomorrow.

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Meredith's confrontation of Lexie trying to take her friends and live her life is so narcissistic. She really needs to get over herself, not just for Lexie's sake, but for Derek. Props to Lexie standing up to her. Even though she appears weak and needy, always wanting to connect with Meredith, she really is the stronger Grey of the two. She just lost her mom, has to deal with an alcoholic father, Yang's consistent scowling at her, and Mer's constant rejection...she still manages to make an effort to right the wrong and avoid blaming others. I think Karev got to see all the pressures Lexie is dealing with all by herself. I hope he's a constant support for her.


It's a stupid comment, but I saw a 'mistake' :
in the beginning of the episode, at 01:34, you can see Mer's breast is covered with something, because the blanket is not in the right position =)


yea..i agree with MB, they just swept it under a rug and forgot all about the Love and chemistry George and Izzie had the first few episodes of S4! and s3...wat happened to the love story written at the start?! they are so meant to be together and it is ruined cause some ppl dun like em as a couple?! wtf?! i miss Gizzie being "in love" and a perfect couple! They might as well hang me upside down!! they are a great couple...and this story line doesn't do them any Justice!! its so shallow and stupidly written! wat was all the kissing and closet scenes about den?! thts chemistry...they just wanted a way out! those who feel the same way...Pls fight for Gizzie.


I disagree with all the pro-Gizzie comments. Izzie and George had 'seemingly' great chemistry when their 'love' for each other was forbidden - while George was married and Izzie was on the verge of losing her best friend. So they had an affair, or one drunken night stand, which the sex was so amazing. Because of that, they started validating all the feelings they had for one another causing George to end his marriage. Now that they have crossed over where the grass is greener, they're starting to realize that it might have been a mistake after all. It's brilliant that the writers are making George and Izzie reap the results of a decision that was made in haste. They are better off being best friends and not lovers.


Seriously. SO WEAK on behalf of the writers. Throwing in a completely nonsensical and heartbreaking plot just to appease whiny fans that have no taste. Where is their sense of integrity about what they believe in and wrote from the start? They wrote us a great couple, hooked us on them, and now make this come out of left field cuz they can't make up their minds. WHat now? George ruined his marriage - oops, by mistake for nothing. I guess all the other amazing chemistry scenes are just supposed to be forgotten. I've lost respect.


they did have chemistry in the previous episodes like with the elevator kiss and the linen closet! i loved those scenes...but i think hannah is saying that in "Physical Attraction, Chemical Reaction" the lastest ep. they killed the chemistry being George and izzie completely! bad sex...and lying at the end of it too. I am a gizzie fan and i want the old chemistry back even if it wasn't in bed!


Completely agree with you Maddison and Hannah! They don't have chemistry? What about the closet scene and the elevator kiss?


Bring back the Gizzie Magic...!! you couple destroyers...c'mon dun we have enough of spoilt relationships?! I can't believe they murdered the chemistry between George and Izzie!! Why?!
I want them to continue to be togther...pls pls.
It ended badly for Gizzie this week...i'm so sad. sob sob.
Gizzie, save them!


OMG....i am firstly so devasted at the ending of the episode. it was a good one with the whole idea of physical chemistry and how ppl are attracted to one another. Liked the lightness it brought with gizzie but the total dramatic touch it brought with the surgeries, and the relationships.
Firstly, i would like to say...I am completely and utterly saddened by the whole Gizzie situation!
it isn't looking good...and tht worries me! cause i love those two being a couple, and all. but they just can't have Good Sex! sighs...they tried so many times and still it was horrible!! even at the end Both of them lied to each other, saying tht it was incredible when it was lousy! *why?!*
the writers shouldn't continue sinking this ship cause i love them being a romantic couple and they just took away everything i loved about them together by havin this barrier!! I really hope tht they dun have any problems after this...and I know they love each other, sadly they can't find chemistry at the moment. Wat happened to the previous eps?! n all tht sexual tension...argh.
Sorry, i'm quite nervous about the whole Gizzie thing since i'm a huge supporter! and it doesn't seem right to put them both in such a situation!
Pls...hopefully something will be resolved and things would be better between them.
although it was funny...until the End!! *shucks*


Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.