Are Alex-Izzie, George-Callie Reunions in Store?
Drs. Karev and Stevens heated up Grey's Anatomy in Season 2, but as we know, it didn't work out. Since then, they've become good friends... but is that it?
At the SAG Awards Monday night, Justin Chambers (Alex) weighed in on a possible Alex-Izzie reunion on Grey's Anatomy, while his Grey's co-star, Sara Ramirez (Callie) hints that there still may be hope for Callie and George.


Would you like to see either or both of these couples back together?
Check out TV Guide reporter Michael Ausiello's SAG video to learn more and to watch his interviews with our favorite stars and others in the TV world.
Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

July 30th, 2008 6:06 PM
alex and izzie are soulmates and are meant to be together i think that callie and george only worked together when georges dad was dying
i HATED the izzie and george pairing and i think that bailey should get someone
i agree seasons 1&2 were the best
June 4th, 2008 3:18 PM
I think that Alex/Izzie should be together but I would have to say no to Callie and George because Callie is too good for him.
Izzie/George in my opinion have best friend chemistry just not hot sexy relationship chemistry. They are better off as friends.
MerDer are adorable and I love them together. I just really want a season where they are together and happy without any interruptions. I feel like they definitely deserve it.
As for Ava, she is crazy. I'm glad she's getting help though.
I love Lexie but I'm also sad that Burke is gone because now Christina is left with no one and I miss the fun Christina.
I hope Season 5 is amazing!
May 13th, 2008 5:08 PM
I don't think the show has gotten that bad. Pretty bad, but not bad enough for me to stop watching. The writer's just think that they need to "spice things up", so to speak. But honestly I just think that ALL of the characters need HEALTHY and somewhat NORMAL relationships. To answer Lisa's question in the last five minutes, Mer is talking to her therapist and says that although the patient didn't get to tell his boyfriend that he loved him before he died, she thought he was being heroic. Her therapist tells her that Meredith is, in essence, that patient. Derek is with Rose and because of that she is "dying alone", and that the reason Derek isn't with her is because she's afraid. Meredith says "Are you calling me a coward?" and the therapist responds "What do you think?". Meredith leaves the room and that is the end of the episode. Alright time for my opinions...
LexZie - hmmmm if izzie hadn't slept with George and Rebecca wasn't being such a bitch and LYING TO HIM about being preg
May 12th, 2008 10:21 AM
I think that izzie and mcsteamy or alex should hook up what do your think
May 9th, 2008 9:54 AM
Can someone please tell me what happened in the last 5 minutes in the show 5/8. I saw Mer talking to her therapist and my DVR stopped recording there.
April 8th, 2008 10:54 PM
george and izzie togetherr!!
alex siempree engaƱaba a izziee =S
March 18th, 2008 8:04 AM
I think that a huge twist should be good for George.
Let him be GAY.............
This would explain his problems in his relationships with woman.
He was also an outsider in his own family with his brothers. He is not the tough guy.
He is sensible and a best friend to the woman in his environment.
Let him hook up with one of the new male characters in the show.
March 2nd, 2008 9:49 PM
GEORGE AND IZZIE BELONG TOGETHER!
February 12th, 2008 4:08 AM
I dont understand why they would put George and Callie together after what happened between them! They suck together. I actually liked the idea of Izzie/George...and not having chemistry??? what the hell is that about? They slept together before and enjoyed it! They had a hot kiss in the elevator! How does chemistry like that all of a sudden disapear? It didnt make any sense, but fine i made my peace with it...but now they are talking about putting george back with callie?? that will ruin the show! He never loved her thats why he cheated! I mean is George! He doesnt cheat...unlike alex at least he loved Izzie, so getting them back together (Even though i dont like the idea) makes more sense. Here's what i think should happen.
(George with Lexie)- They would actually make a cute couple...
(Derek/ Meredith)- For the love of god, either get them married or have them brake up for good already! Meredith needs to stop whining and realize that she has a good man who loves her...she makes
February 11th, 2008 6:14 PM
I think that George and Merideth should actually be a couple. Izzie and Alex shouldn't happen, and George and Callie definetly shouldn't happen.