Patrick Dempsey's Keys to Relationship Success

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The man known as Dr. McDreamy may not know how to make a marriage last on Grey's Anatomy â€" but the man known as Patrick Dempsey sure does!

"Love, humor, communication. To me those are the bedrocks of a good relationship," the Versace-clad Dempsey, 42, said Monday at the New York City premiere of his wedding-themed romantic comedy, Made of Honor.

Dempsey at the Premiere

The Grey's Anatomy star plays a compulsive womanizer in the comedy, but says the Made of Honor character's "nothing like me at all â€" I'm married and have kids!"

Of his wife, Jillian Dempsey, the appreciative father-of-three said:

"She's immensely supportive. Without her, I wouldn't be here."

They have a six-year-old daughter and one-year-old twin sons.

So does Patrick Dempsey â€" who was recently featured in USA Today among other publications â€" have any funny memories from their 1999 nuptials?

"The photographers were drunk and never got a good picture!" he joked.

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Lmao.! The hair! That's not what it used to be...

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Oh man this picture. He looooooooookkkkksss Sooooooooo GOOOD! :)

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How many interviews is he doing??? It is his new full-time job??? And he's always saying the same things: "i love my wife" (that begin to seem fake to me at this point) and "please see my movie". I am getting tired.

Grey's Anatomy Quotes

Just because we can live without something, it doesn't mean we have to.

Meredith

Derek: I am calling post-it, Zola, Bailey, the tumors on the wall, ferryboat scrub caps. I thought D.C. was everything. I was wrong. You... you're everything. I love you and I'm not going to stop loving you. I can't live without you. I don't want to live without you, and I'm going to do everything in my power to prove it.
Meredith: I can live without you, but I don't want to. I don't ever want to.