Gossip Girl star Leighton Meester was seen with her entourage Wednesday - but not on the Upper East Side. Try West Hollywood!

The 22-year-old actress took a break from filming Gossip Girl and shot a new episode with Adrian Grenier for HBO's Entourage.

It's a new Entourage for Leighton Meester this week.

Leighton Meester will be reprising her role from the first season of the HBO series - she played then-virginal pop singer Justine Chapin.

Looks like the chemistry between Justine and Vinnie is hotter than ever! Click here for more pics of Leighton on the Entourage set.

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.