Grey's Anatomy Spoilers: The Wedding, George's Exit, Etc.

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There's a wedding coming up on Grey's Anatomy's 100th episode on May 7 - and the McDreamy gentleman pictured below will not be participating! So who is?!

Owen and Cristina certainly connect physically tonight - but not in a good way whatsoever. Seriously, dude has issues, and she's bearing the brunt of them.

George, in a rare appearance on the show, takes an interest in a new surgical field and is taken under Owen's wing. Is this setting the stage for his departure?

Follow the link for much more on these Grey's Anatomy spoilers!

Just Leave, Meredith!

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Grey's Anatomy Quotes

CRISTINA: "There's a club. The Dead Dads Club. And you can't be in it until you're in it. You can try to understand, you can sympathize. But until you feel that loss... My dad died when I was nine. George, I'm really sorry you had to join the club."
GEORGE: "I... I don't know how to exist in a world where my dad doesn't."
CRISTINA: "Yeah, that never really changes."

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."