There's a wedding coming up on Grey's Anatomy's 100th episode on May 7 - and the McDreamy gentleman pictured below will not be participating! So who is?!

Owen and Cristina certainly connect physically tonight - but not in a good way whatsoever. Seriously, dude has issues, and she's bearing the brunt of them.

George, in a rare appearance on the show, takes an interest in a new surgical field and is taken under Owen's wing. Is this setting the stage for his departure?

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