Grey's Anatomy returns for its sixth season with a two-hour event Thursday, September 24, on ABC. Below is the network's official synopsis of the Season 6 premiere.
Technically, the event is listed as two separate episodes, both written by Krista Vernoff and featuring Jessica Capshaw as an official cast member for the first time.
The first episode, entitled "Good Mourning," will air at 9 p.m.
The hospital staff is left to deal with the aftermath of George's passing. Hitting the staff hard, they all find unique ways to get through the various stages of grief.
George's mom returns, faced with the difficult task of deciding what to do with his organs.
The second episode, entitled "Goodbye," follows at 10 p.m.
As this episode begins, time has passed. Everyone at Seattle Grace Hospital is struggling after losing one of their own and are turning to any distraction they can find.
Meredith and Derek are consummating their marriage anywhere and everywhere, while Cristina and Owen have been instructed to abstain from sex by Dr. Wyatt.
Guest stars for "Good Mourning" are Shannon Lucio as Amanda (the woman George saved at the end of last season), Debra Monk as Mrs. O'Malley, Martha Plimpton as Pam, Mitch Pileggi as Larry Jennings, Zoe Boyle as Clara and Zack Shada as Andy.
Grey's Anatomy guest stars for "Goodbye" include Amy Madigan as Dr. Wyatt, Adam Lazarre White as an Oncology Resident, Lucio, Plimpton, Pileggi, Boyle and Shada.
"Good Mourning" was written by Krista Vernoff and directed by Ed Ornelas.
"Goodbye" was also written by Vernoff but directed by Bill D'Elia.