We know she survives her cancer operation, but how does Izzie handle her condition and treatment as Season Six of Grey's Anatomy begins and progresses?

She'll be meeting with a cancer support group, which helps. But what about the toll it takes on her marriage to Alex? How does she cope with George's death?

Does it culminate in her firing from Seattle Grace, and Katherine Heigl's announced five-episode hiatus from the show she's been rumored to hate forever?

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