An art dealer living in New York City, Simone Deveaux is originally introduced as the girlfriend of Isaac Mendez.But her dying father's nurse, Peter Petrelli, has a crush on Simone and the two of them eventually get together. Simone believes in Peter's powers and supports his cause.When Peter goes missing, Simone tries to enlist Isaac's help. But the love triangle becomes dangerous and Mendez ends up shooting Simone in an attempt to kill Peter.
Isaac Mendez: I don't want to lose you. But if you don't believe in me you shouldn't be here.
Simone Deveraux: Fine. You think you can paint the future, paint one without me in it.
Simone Deveraux: You know, I don't know what he'd do without you - you've got a real gift.
Peter Petrelli: I just do my job.
Simone Deveraux: No, you're like a son to him.
Peter Petrelli: Yeah, but that'd make us like brother and sister and that might be a little awkward if I ever wanted to ask you out.