Okay, so some nicknames are better than others. But we love Lexie and Callie so much, we had to try.
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Hunt and Callie are on the case as an accident admits many new visitors to the ER.
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Owen and Callie are on the scene as a trauma arrives at Seattle Grace. And it looks like it's going to be a big one.
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Callie Torres in the Grey's Anatomy Season 5 finale.
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Callie and Arizona certainly qualify as that. Whether you believe they are really lesbians or not, the acting by Jessica Capshaw and Sara Ramirez is terrific.
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Calliope Torres has been disowned by her family, but she loves Arizona, and she loves her work. We think this talented doctor will be okay.
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Arizona and Callie are one of Grey's Anatomy's newest and most controversial couples. They're doing better lately, although there is always a crisis around the corner.
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Callie and Arizona (Calzona) at the wedding of Alex and Izzie. Having gotten over their nonsensical fight over Callie's money problems, the two are back on good terms.
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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith