The doctor is in ... our hearts
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Derek is inconsolable at the thought of losing Meredith.
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A concerned doctor
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Derek Shepherd proved to be Richard's choice for Chief, and also a good friend to Preston.
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Derek Shepherd will serve as Preston Burke's best man. But they're both the best in our book.
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Does Derek know anything but?
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At patients, that is.
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There's only one Derek Shepherd.
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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith