The Season Four cast of Grey's Anatomy: Starring the lovely Ellen Pompeo (Meredith Grey), Patrick Dempsey (Derek Shepherd), Sandra Oh (Cristina Yang), Katherine Heigl (Izzie Stevens), T.R. Knight (George O’Malley), Justin Chambers (Alex Karev), Chandra Wilson (Miranda Bailey), James Pickens, Jr. (Richard Webber), Sara Ramirez (Callie Torres), Eric Dane (Mark Sloan) and Chyler Leigh (Lexie Grey).

Richard Webber, Meredith Grey and Derek Shepherd study some information. No word on whether Mer and Der study each other later on.

Chief's wife, Adele, is back at Seattle Grace. And not for a reason that's positive... their niece is again sick.

It isn't easy for Dr. Richard Webber, who runs the show over at Seattle Grace. His marriage has suffered and the trials of the job put constant strain on him.

Dr. Richard Webber (James Pickens, Jr.) is once again at the center of marital and professional problems as Chief of Surgery on Grey's Anatomy. In "The Heart of the Matter," Adele returns and their niece is once again in failing health.

Yes, it does. To us all. To Adele, especially. But does it matter enough to Dr. Richard Webber? We'll see as the Chief treats his sick niece.

Richard talks with George and Lexie about a patient. The Chief is always a steady, strong presence at the hospital.

Richard is determined to get back in the swings of things in his personal life. Whether he can accomplish that is another story.

Studying the data, Meredith, Derek and Richard work on a case together at Seattle Grace. What a good trio to have working for you as a patient.

Bailey and the Chief do what they can to sedate and save a patient that Miranda knows from way back in the day. Will they succeed?

We mean the ambulance in the background, of course... not the Chief. He's the one who's got to keep this place running!

Charlotte and Pete chat about medicine, family, etc., in an attempt to get the bossy St. Ambrose Chief of Staff to get some shut eye.