S and S in a photo from "High Infidelity." The second episode of Gossip Girl's final season airs October 15, 2012.
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Serena and Nate in a photo from "High Infidelity." The second episode of Gossip Girl's final season airs October 15, 2012.
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Blake Lively as Serena in a photo from the much-anticipated sixth and final season premiere of Gossip Girl. "Gone Maybe Gone" airs October 8, 2012.
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Serena is getting married, or so it appears, in this photo from the final season premiere of Gossip Girl. "Gone Maybe Gone" airs October 8, 2012.
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How will Serena respond to losing her status as Gossip Girl? We will find out in "The Fugitives."
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Blake Lively as Serena van der Woodsen in a photo from the April 23 episode of Gossip Girl, "Despicable B."
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Serena and William having a conversation in the April 23 episode of Gossip Girl, "Despicable B."
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Serena and Lily in the April 23 episode of Gossip Girl, "Despicable B."
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Gossip Girl Quotes

Don't ever go to high school, Dorota. The girls are spoiled, stupid and ungrateful! One snapshot with a socialite and it's all Serena, Serena, Serena!

Blair

Gossip Girl: Sorry, boys. But didn't you know that if you wait to long to seize the day—
Chuck: Gone.
Louis: Where would she go?
Gossip Girl: The one you want could get away.