Grey's Anatomy

Thursdays 8:00 PM on ABC
Greys anatomy
Meredith & Derek
The only couple on this list who actually hooked up prior to the series ever starting, Grey's Anatomy kicked off the morning after Meredith and Derek went home from a bar together. Sure, he was married at the time - but that technicality was no match in the end for (sorry we have to say it...) the McDreamiest pairing on all of television.

Rating: 5.0 / 5.0 (69 Votes)
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Grey's Anatomy Photos, Meredith Grey Photos, Derek Shepherd Photos
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Grey's Anatomy Quotes

Our lives are built on our mistakes as much as our successes.

Ellis

They say we can repress our memories. I wonder if we're just keeping them safe somewhere because no matter how painful they are, they are our most valuable possessions. They made us who we are.

Meredith
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