Derek Shepherd, a.k.a. McDreamy, has been one of the core characters from the beginning. Grey's Anatomy isn't Grey's Anatomy without Derek Shepherd (Patrick Dempsey).

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Grey's Anatomy Quotes

COOPER: "It's wrong?"
NAOMI: "You need to meet a grown up. You need to date someone your own age."
VIOLET: "Someone without a porny internet name and perhaps no criminal past."
NAOMI: "A nice girl."
VIOLET: "A reliable girl."
NAOMI: "Someone who you can have a relationship with."
VIOLET: "You’re a respected doctor."
NAOMI: "Go out in the real world. Meet a woman your own age and go out."
VIOLET: "Be a man."

ADDISON: "You work with your ex-husband in a shrine for your ex-husband."
NAOMI: "It’s actually a good book. And we're friends. And we stayed friends after we divorced. It’s very healthy. We're healthy."
ADDISON: "What happened between you and Sam?"
NAOMI: "Addison, you and I were close in med school, but it was a long time ago."
ADDISON: "Oh, Naomi. Come on. You can’t stay mad at me forever. I know you."