Grey's Anatomy Cast: Before the Were Stars

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Take a walk down memory lane as we look at the cast of Grey's Anatomy before they were stars.

1. Grey's Cast Photo

Grey's Cast Photo
One thing you can always count on is the cast of Grey's Anatomy will continue to change to keep things fresh. We'll look at the stars of Season 11 and where they've been before they hit it big.

2. Patrick Dempsey as Derek Shepherd

Patrick Dempsey as Derek Shepherd
Dempsey joined Grey's in 2005 instantly becoming McDreamy Derek Shepherd. Before that he had a role in The Practice (2004) - also as a doctor - as well as a part in Once and Again (2000-2002) as Aaron Brooks. He was known more for movies than television until Grey's.

3. Patrick Dempsey in Can't Buy Me Love

Patrick Dempsey in Can't Buy Me Love
In 1987 Dempsey went from dorky to dreamy as the lawnboy who went to great lengths to win the heart of the popular girl next door. I don't know any girl from that time who didn't want to be Amanda Peterson who starred as Cindy Mancini. Sidenote - Seth Green costarred!

4. Patrick Dempsey in Heaven Help Us

Patrick Dempsey in Heaven Help Us
Dempsey's first role was in Heaven Help Us (1985) as Corbet. A movie about catholic school boys starring Donald Sutherland, Andrew McCarthy, Mary Stuart Masterson and Kevin Dillon. Not bad for a first credit, right?!

5. Ellen Pompeo as Meredith Grey

Ellen Pompeo as Meredith Grey
Prior to Grey's Pompeo made her first splash in movies, most notably Moonlight Mile (2002) with Dustin Hoffman, Susan Sarandon and Jake Gyllenhaal.

6. Ellen Pompeo in Strangers with Candy

Ellen Pompeo in Strangers with Candy
One of Pompeo's first credited roles was in Strangers with Candy as Lizzie Abrams in an episode titled Feathers in the Storm (1999). Candy was a comedy show starring Stephen Colbert and Amy Sedaris.

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Grey's Anatomy Quotes

Amelia: I think I'm falling in love with Owen Hunt, and I'm really afraid that it's gonna destroy me.
Derek: It wouldn't be love if it didn't.

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith