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Tonight, Grey's Anatomy returns with an all-new episode (its 18th of the season), "Stand By Me." Check out the spoilers and previews posted earlier today for a primer!

Izzie Stevens' ailment is hard to keep secret, especially when the one person who knows is Cristina. Speaking of Yang, she is about to attempt her first solo surgery.

Oh, and there's the McDreamy matter. He's off in the woods, unable to find it within himself to return to work. He's fallen apart. Can anyone put him back together?

We can't wait to find out, and hear what you have to say about everything.

As always, you can discuss "Stand By Me" before, during and after the episode in our
Yang and Hunt

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.


Grey's Anatomy Quotes

Arizona: Oh my God! I mean, I understand why you're into her. She's hot. Wait, she likes you?
Nathan: What? I mean, I'm going to try not to be offended at that.
Arizona: No, no, no. It's just that Derek was--Derek was epic for her. They were the great love story. I mean, that girl's heart beat for Derek Shepherd. It just...it never occurred to me that she would ever be with anyone else. He was perfect. He was everything. That man turned her world. It...I spooked you. Don't be spooked.

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."