If you’re not a fan of Grey's Anatomy spoilers, avert your eyes. But if you’re down with knowing the details and truth directly from the actors, then read on!

Izzie’s (Katherine Heigl) condition is solved by the interns in the next Grey's Anatomy (the March 12 episode), according to Justin Chambers (Alex Karev).

“Izzie has cancer, so I’m there to support her,” he tells TV Guide.

There you go.

With all the trials and tribulations that have befallen Izzie Stevens lately - the return of the ghost of Denny Duquette, sex with the ghost of Denny Duquette, making crafts for her team of interns - this probably doesn’t come as a major surprise.

But to actually hear the word “cancer” from Justin Chambers, who plays her love interest, confirms what viewers probably knew for months sensed was coming.

The actor says that Alex and the rest of the Seattle Grace gang are going to have their hands full as they help their friend Izzie deal with her upcoming battle.

“I would expect Alex to shut down a little bit if something awful happens to Izzie, but these are opportunities to see his chivalrous side and his true love for her, so there should be some interesting stuff coming up,” says Chambers.

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.