Stewie starts going to the gym with Peter after he gets beaten up by Joe’s baby daughter Susie. He gets pretty ripped, but Peter reveals that he’s been giving him steroids.

After Brian is arrested for drug possession he launches a campaign to legalize marijuana. Mayor Adam West passes the law and the whole town goes to pot. Brian then protests to re-ban marijuana and Mayor Adam West passes the law.

Meg becomes a born-again Christian and tries to convert Brian from atheism. Meanwhile Stewie is furious that he doesn’t get to ask the cast of Star Trek: The Next Generation any questions at a convention so he kidnaps the cast and forces them to hang out with him.

Lois lands a job at Fox News and has to shoot an investigative exposé on Michael Moore but loses her job when her story implicates Rush Limbaugh instead.

Peter cashes in an old raffle ticket from 1989 and wins a golf outing with O.J. Simpson, who he befriends Simpson and brings him home to meet the family. Quahog as a whole is not too pleased.

Peter participates in some medical experiments to pay off his debt made by a mentally disabled horse including one that sees him getting injected with the “gay gene.”

Bonnie finally gives birth to her baby, a girl named Susie, with whom Stewie falls for and will do anything to win over her heart. Meanwhile Joe borrows $20,000 with a plan to pay off the debt.

Peter does everything so he can to receive a promotion at work but he must first be sent back to repeat the third grade in order to qualify. Meanwhile Frank Sinatra, Jr. returns to Quahog to buy the local nightclub with Brian.

When Brian gets injured during a take of Peter’s version of Jackass the Griffins realize that Brian may be getting too old so Peter brings home a new dog prompting Brian to leave.

Peter gets a lasting supply of gasoline for the year so the family decides to use it to take a road trip to the Grand Canyon.