Lexie Grey is the daughter of Thatcher and Susan Grey (who passed away at the end of Season 3), and thus the younger half-sister of Meredith Grey. She also has a younger sister, Molly Grey Thompson.

Lexie is a graduate of Harvard Medical School.

At the end of Season 3 of Grey's Anatomy we learn that Lexie Grey will be a new intern at Seattle Grace. She was introduced in the penultimate episode of the third season as a woman Derek Shepherd met at the Emerald City Bar.

In the season finale, Derek confessed to Meredith that he met another woman (although he still doesn't specify who) and when she asks if she should be worried, he confirms her fears. While he didn't get together with Lexie, Derek admits meeting her was the highlight of his day.

Lexie Grey later made her first appearance in Seattle Grace when she introduced herself to George O'Malley, who was cleaning out his locker as she was on her way in. Upon hearing the name Lexie Grey, George clearly realized her connection to Meredith. What's to come of this new intern?

Lexie Grey Quotes

Lexie: The point is - I need to know what we are. What this is.
Alex: We're a thing, yeah we're together. We're a thing. Whatever.

That a hooker on your shoulder?

Lexie

Grey's Anatomy Quotes

CRISTINA: "There's a club. The Dead Dads Club. And you can't be in it until you're in it. You can try to understand, you can sympathize. But until you feel that loss... My dad died when I was nine. George, I'm really sorry you had to join the club."
GEORGE: "I... I don't know how to exist in a world where my dad doesn't."
CRISTINA: "Yeah, that never really changes."

The brain is the human body's most mysterious organ. It learns. It changes. It adapts. It tells us what we see, what we hear. It lets us feel love. I think it holds our soul. And no matter how much research we do, no one can really say how all that delicate grey matter inside our skull works. And, when it's hurt, when the human brain is traumatized, well, that's when it gets even more mysterious.

Callie