Natalie Vega was born to Clint and Viki Buchanan along with her half-sister, Jessica. Jessica's father, Mitch Laurence (who had secretly raped Viki, information that did not get out for years), had no use for Natalie (Clint's daughter) and shipped her off to live with his cohort, Dr. Balsom...

Mothers: Viki Davidson (biological), Roxanne Balsom (adoptive)
Father: Clint Buchanan
Siblings: Kevin Buchanan (half-brother), Joey Buchanan (half-brother), Jessica Buchanan (half-sister), Megan Gordon (half-sister; deceased), Cord Roberts (half-brother), Rex Balsom (adoptive)
Grandmothers: Olympia Buchanan (deceased), Eugenia Lord (deceased), Stella (adoptive)
Grandfathers: Asa Buchanan, Victor Lord (deceased)
Nieces: Sarah "Flash" Roberts, Megan Buchanan (deceased), Brennan Buchanan (deceased)
Nephews: Duke Buchanan (deceased), CJ Roberts
Uncles: Bo Buchanan, Tony Lord (deceased), Todd Manning, Ben Davidson (deceased)
Aunts: Tina Clayton Lord, Meredith Lord Wolek (deceased)
Cousins: Matthew Rappaport, Drew Buchanan (deceased), Starr Manning, Jack Manning, Sarah "Flash" Roberts, CJ Roberts, Danny Wolek, Brian Kendall (deceased), Tommy McBain
Brother-in-law: Antonio Vega
Significant Romantic Relationships: Seth Anderson, Mitch Laurence (1st husband/annulled), Cristian Vega (2nd husband/divorced), John McBain, Paul Cramer