George and Izzie will always be close, even though their relationship has been through its ups and downs. What a wonderfully-written scene this was, when he helped her down the aisle.
Izzie stumbled on her way down the aisle, but George stepped in and helped his old friend make it to the steps, where she exchanged vows with Alex. Tear.
It was a sweet scene when George gave away Izzie to Alex at the wedding, when she became weak and could not walk under her own power. Tears were shed at this website.