J.D. ends up sleeping with Neena (Julianna Margulies) and can't end things with her despite her suing his best friend.

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Scrubs
Episode:
Scrubs Season 4 Episode 10: "My Female Trouble"
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Scrubs Season 4 Episode 10 Quotes

J.D.'s Narration: No matter how much we like to pretend otherwise, strong confident women will always have the power over us. Whether they're fighting for respect, fighting for their man, or even just fighting for the hell of it. Strong women make all guys feel the same way.
The three women walking down the hall, past the guys who turn into little boys.
Little Cox: Jordan looks mad, I should go.
Little Turk: I have to pick up Carla's dry-cleaning.
Janitor: Well, what do we have here?
Little J.D.: Oh, no.
Janitor: I heard from a reliable source that you want to live in dumpster. I can arrange that. Yep, I know just the right neighborhood.

J.D.: Neena, it's over.
Neena: No it's not. In fact, I find myself oddly turned on by your timid, baby horse standing up for the first time style of humping.
J.D.: First of all, thank you. Secondly, I've tried to be reasonable, now if you wanna see my dark side, you're gonna see my dark side.
(J.D. starts softly tickling Neena)
J.D.: Ah tickle tickle tickle. Ah tickle tickle tickle tickle.
Neena: Yet another strong moment for ya.