Here we have a brilliant cardio-thoracic surgeon and solid all-around guy

George O'Malley has been largely absent from Grey's Anatomy this season. What gives?

Nathan is no McDreamy, but he's quite dashing and has really great hair, too.

Check out this classic photo of Erica Hahn from way back when.

Mark Sloan in "These Arms of Mine." The Grey's Anatomy episode October 28 will show us the doctors like we've never seen them before.

This is the key art released for Grey's Anatomy Season 18.

A photo of Lexie in the February 16, 2012 episode of Grey's Anatomy. It's titled "Have You Seen Me Lately?"

Mark Sloan shows up on Meredith's Beach in her dreamscape along with Lexie and both talk to her about life.

Dr. Derek Shepherd in the Season 9 episode "Transplant Wasteland."

Similarly to previously mentioned characters, Callie also comes from a strictly Catholic Latina background. She has a more difficult coming out process as her father first disowns her after hearing the news, but eventually he learns that no amount of praying will pray the gay away. With the help of her girlfriend Arizona, she's able to truly embrace her sexuality and show us that being gay is not simply a choice.

We're close up with Dr. April Kepner in this Grey's Anatomy scene. She'll play a key role on Season 11.

Seriously, look at this guy! He's so attractive it's offensive. How does he always find his light? Why is his smile so perfect? Beauty, brains, and the personality to match. Jackson Avery is the full package, ladies, gents, and all those in between.