Arizona tries to reconcile with Callie, who has big news to share. Teddy faces an important decision; the residents receive new interns; the Chief makes an announcement.

News of the incoming mass causalities after a gunman opens fire at a local college hits the staff hard when they must spring into action, even while their own wounds are still fresh.

Despite Meredith’s objections, Derek takes Cristina on a fishing trip in order to get away from it all. Teddy directs all her efforts towards a dying patient who lacks insurance to seek medical treatment.

Derek lands the grant he needs for his clinical trial, but a surprise visitor shakes up the celebration at Joe’s. Meredith and Alex have to fend for themselves during the night shift.

Top security measures go into place as the team treats a major political figure from the Middle East. Cristina throws a housewarming party. Alex shows up late from a weekend getaway to his first day of rounds with the new Pediatrics Attending.

The residents are pushed to their limits when Owen puts them through a rigorous trauma drill; Cristina is tested when left alone to monitor a lung transplant patient.

A documentary film crew visits the hospital six months after the shooting to document the road to recovery for doctors and patients. What follows is a trip down memory lane, and not in a good way.

Chandra Wilson (Bailey) makes her second directorial mark on Grey’s Anatomy in this episode, the fifth of the seventh season.

A visit to the obstetrician results in some disturbing news for Meredith and Derek. Lexie loses it when she notices Meredith and April getting closer.

Derek receives an unexpected and unwelcome visit from his estranged sister, Amelia, and issues between the siblings – both past and present – surface in the latest Private Practice crossover event.