DEREK: "Can you keep a secret?"
MEREDITH: "Better than you think."

PRESTON: "Why are you in this line?"
CRISTINA: "It’s the syphilis line."
PRESTON: "You don’t need to be in this line."
CRISTINA: "I don’t?"
PRESTON: "There’s no one else. That surprises you?"
CRISTINA: "Nothing surprises me."
PRESTON: "Do I need to be in this line?"
CRISTINA: "No."
PRESTON: "Okay then."
CRISTINA: "Okay."

CRISTINA: "You know, I think he really likes Typhoid Mary."
MEREDITH: "Not many budding relationships survive a good dose of VD."

CRISTINA: "Oh, what are we doing?"
IZZIE: "We are saving George from a future of festering sores and insanity."
CRISTINA: "Cute butt."
MEREDITH: "Told you."
IZZIE: "It is cute. Like a baby's."
GEORGE: "You know I've spent hours, days, years, imagining myself half naked in a room with three women? The reality is so much better."

GEORGE: "You know what? Forget this."
ALEX: "Hey, do you wanna get rid of the syph or not? Then shut up and drop it."
GEORGE: "Can't believe I'm doing this." [sees Mer] "Meredith! Go away!"
MEREDITH: "Oh, George. I thought you could use some moral support."
GEORGE: "No. No moral support. I'm indisposed here!"
MEREDITH: "George. It's not a big deal. And you have a cute butt."
ALEX: "I have a cute butt too. Want to see?"
MEREDITH: "Oh, get out. You're doing it wrong."
ALEX: "Be my guest."
GEORGE: "What? Alex. Alex! What!? Hey!"

GEORGE: "Are you sure you know what you're doing?"
ALEX: "It's a shot of penicillin, George. Be grateful that I am doing this. I've already seen more of you than I ever wanted to. I'll fight the nightmares for a week."

ALEX: "Everybody’s got a secret. Just be glad yours is out in the open."
CRISTINA: "Oh yeah, Alex? What’s yours?"
ALEX: "Show me yours and I'll show you mine. I bet you've got some seriously kinky skeletons in your closet."
CRISTINA: "What’s in my closet is none of your business."
IZZIE: "Well, I don't have any secrets, my life is boring."
MEREDITH: "Everybody’s got something to hide."

CRISTINA: "Hey, Syph-boy!"
GEORGE: "You told her?"
IZZIE: "Just Cristina."
ALEX: [smirks] "Syph-boy. It's got a nice ring to it. Kind of like Super-boy, only diseased."

GEORGE: "God, he's got an ovary?"
ALEX: "Gives a whole new meaning to metrosexual."

[to George] "Who gave you the cooties on the playground?"

ALEX

GEORGE: "Oh yeah? How am I gonna tell her? 'Hey Olivia, how are you? Oh, by the way, I got the syph. How about you?'"
IZZIE: "Well, maybe not quite like that."
GEORGE: "No, no! It’s good advice. Really good advice, thank you very much."

GEORGE: "What am I gonna do about Olivia?"
IZZIE: "Well, for starters, stop sleeping with her. Unless, you want that thing to fall off."
GEORGE: "That's twice that you trash talked the girl I could one day potentially lo- well, not love, but like a whole lot."
IZZIE: "If she gave it to you, you have to tell her."
GEORGE: "Three."
IZZIE: "Fine! She didn’t give it to you. She was a virgin when you met. You still have to tell her so she can get tested."

Grey's Anatomy Season 1 Quotes

"If I miss a real procedure because of this case, they're gonna call me 007, because I killed you."

CRISTINA

ALEX: "Morning, Dr. Model."
IZZIE: "Dr. Evil Spawn."
ALEX: "Ooooh, nice tat. Do they airbrush that out for the catalogs?"
IZZIE: "I don't know. What do they do for the 666 on your skull?"