GEORGE: "You don’t know. Maybe I’ve been sleeping around. Maybe I got ladies."
IZZIE: [smirks]
GEORGE: "Shut up! What am I gonna do?"
IZZIE: "It’s no biggie. A couple doses of penicillin will knock it right out."

IZZIE: "You got syphilis?"
GEORGE: "I don’t know how this happened."
IZZIE: "Of course you do. God, Olivia must be really getting around!"
GEORGE: "Olivia, she’s not like that."
IZZIE: "It’s the new millennium, George. The only people who aren’t like that are the Amish... and apparently you."

"I know I’m pretty to look at and all, George, but back up."

ALEX

IZZIE: "You know what? It's no big deal, you don't have to lie. I get it. You have needs."
MEREDITH: "What is going on out here?"
GEORGE: "Nothing." [walks away]
IZZIE: [to Meredith] "He's freaked out because I caught him playing with little Jimmy and the twins."
GEORGE: [Turns around] "I have a girlfriend!"
IZZIE: [laughs] "Okay."
DEREK [walks out of Meredith's room] "It sounds like fun out here."

IZZIE: "There's no reason to be ashamed. It's normal, healthy even."
GEORGE: "I am not ashamed. 'Cause I wasn't doing anything. I don't have to. I have a girlfriend."
IZZIE: "An imaginary girlfriend?"
GEORGE: "An actual girlfriend."

IZZIE: [knocks] "George. You locked the door I need to take a shower."
GEORGE: "Um... uh, I'll be out in a minute."
IZZIE: "What are you doing in there?"
GEORGE: "It's private!"
IZZIE: "Oh! Oh, God, I get it. I'm sorry." [Smirks] "I didn't mean to interrupt."
GEORGE: "No, it's not that."
IZZIE: "It's okay. Take your time!"
GEORGE: "I am not doing what you think I'm doing."
IZZIE: [laughs] "You know what, there really isn't a need to explain. Just... finish."
GEORGE: "No... I'm coming. Coming out!
IZZIE: [laughs]

[narrating] "Secrets can't hide in science. Medicine has a way of exposing lies. Within the walls of the hospital, the truth is stripped bare. How we keep our secrets outside the hospital -- well, that’s a little different. One thing is certain, whatever it is we're trying to hide; we're never ready for that moment when the truth gets naked. That's the problem with secrets -- like misery, they love company. They pile up and up until they take over everything, until you don't have room for anything else, until you're so full of secrets you feel like you're going to burst."

MEREDITH

[narrating] "But the thing is, it’s hard to let go of that fairy tale entirely, because almost everyone has that smallest bit of faith and hope that one day they would open their eyes and it would all come true. At the end of the day, faith is a funny thing. It turns up when you don’t really expect it. It’s like one day you realize that the fairy tale is slightly different than your dream. The castle, well it may not be a castle. And it’s not so important that it’s happily ever after -- just that it’s happy right now. See, once in a while, once in a blue moon, people will surprise you. And once in awhile, people may even take your breath away."

MEREDITH

[to himself] "This is George, George has a hot date."

GEORGE

MEREDITH: "I tried to talk Dr. Shepherd out of that clot surgery. What is wrong with me?"
ALEX: "Basically, you tried to kill a guy."
CRISTINA: [to Alex] "Basically, you're an ass."

CANCER PATIENT: "It’s our decision and that’s okay."
CRISTINA: "So why do you need my approval?"
CANCER PATIENT: "I just want you to understand."
CRISTINA: "Well, I don’t."

MEREDITH: "You know, you keep taking everything on faith. How do you know what’s real and what’s not?"
DEREK: "You just do. You know some people would call this a relationship. Time to exchange keys, leave your toothbrush over."
MEREDITH: "Who, who would call it that?"
DEREK: "Me, I would."
MEREDITH: "And I’m supposed to believe you. Show me something. Give me a reason to believe."

Grey's Anatomy Season 1 Quotes

"If I miss a real procedure because of this case, they're gonna call me 007, because I killed you."

CRISTINA

ALEX: "Morning, Dr. Model."
IZZIE: "Dr. Evil Spawn."
ALEX: "Ooooh, nice tat. Do they airbrush that out for the catalogs?"
IZZIE: "I don't know. What do they do for the 666 on your skull?"