George O'Malley died.

Cristina

Owen: I don't wanna hurt you again. My problems they're real, and this, this makes us real. It makes my problems your problems. I'm afraid. I don't wanna hurt you again.
Cristina: You can sleep in the bathtub.
Owen: What?

Look, I am an attending. And, I am a single mother. And I lost O'Malley. And um, I just can't. I can't care anymore. Stevens is not my child. O'Malley was not my child. I have to stop treating them... I just have to stop caring so much. 'Cause I can't keep feeling... feeling like this. Not at work. I have to save the feeling for my son, who needs it. I just can't keep giving it away here. I can't. I won't.

Bailey

Cristina: I... I can't get back on Bailey's service. I mean, she's still not even looking at me.
Owen: Cristina, give it time. I mean, you know, she was closer to O'Malley and she has more...
Cristina: Yeah, I know but she's... it's not even about O'Malley. She's mad at me about Ceviche.
Owen: (laughing) You've gotta stop that.
Dr Wyatt: Ceviche?
Cristina: It's a patient.
Owen: Ah, a boating accident victim. She thinks that it's ok to call her a seafood dish. Is that ok?
Dr Wyatt: Well, it's pretty dark.
Cristina: Oh come on. I'm dark? I'm not the one going around choking people in their sleep.

Alex: Is there some kind of time line on this. Or...
Doctor: Your wife is living with cancer Dr Karev. Right now, the cancer has stopped growing. With a cancer this aggressive, that's pretty stunning success. There's not time line. There's just... we watch it. We wait. We hope it doesn't start to grow again.
Izzie: That's it?
Doctor: That's it.

Lexie: I'm worried about Clara. She's depressed, but like a whole new level of depressed. I don't know what to do.
Cristina: Are you talking about Ceviche?
Lexie: That... (Cristina signs the propeller hitting Clara's stomach) Oh my god! That's... that is so rude. Ceviche? That is so... that... it... that... that's rude. That is SO RUDE!
Cristina: What? Anyone else I can offend?

Meredith: I haven't cried yet. I'm using work and sex as a distraction and I think it's working for me. Have you seen the girl Amanda? She's sitting outside the hospital on that bench all day long. It...
Cristina: I miss sex. UGH! I miss it so much! (Mer gets up to leave) What? Mer!

Richard: Shepherd?
Derek: You're a hard man to track down.
Richard: I'm busy, as you know.
Derek: Yeah, scoping out Mercy West. You planning on jumping ship? 'Cause I assume as a friend you would tell me if there's anything I need to know.
Richard: Those are rumors Derek.
Derek: There are a lot of rumors, and Jennings isn't answering my calls anymore.
Richard: Why are you calling Jennings Derek? I told you I would fill you in when there was something to tell. If you feel the need to go behind my back, at least do...
Derek: Behind your back? Behind your back! I'm the one whose got your back. Don't you forget that.

Lexie: Are you really gay? Like, how gay are you? On a scale of 1 to gay? 'Cause that's my boyfriend in the shower. My hot, hot, naked boyfriend and I... How gay are you?
Callie: I'm sorry. It's... I've known Mark a while and... But, I'll try not to do that again. The naked in the shower thing.
Lexie: Or, the you half naked in the hallway thing. Cause, cause even if you really are gay. He's not, and you're hot.
Callie: He doesn't look at my boobs anymore. The first thing he used to look at when I walked into anywhere, was my boobs. He doesn't look anymore. Not since he met you. Ok?
Lexie: Ok.

Izzie: Whatcha reading?
Alex: I have this patient I'm trying to diagnose. It's driving me nuts.
Izzie: So take a break, I miss you.
Alex: I'm right here.
Izzie: No you're not. You're here, but you're not here. And I miss you.
Alex: Iz, come on. I'm trying to work.
Izzie: I'm wishing for a brain tumor. I'm wishing all the time for a giant tumor that would just press down on my brain and make me hallucinate George. So that I could talk to him again, so I could laugh with him again. I miss him so much. I miss him all the time, and I just want to feel better. Even for a minute you know, I just want to be a person who isn't wishing for a brain tumor. Just for one minute. And, I can't drink because of the cancer meds, I don't do drugs, I can't even work right now. I don't have any distractions. I'm sad, and I miss George. So please, please, come inside and help me feel better.
Alex: "I miss George". Nice. Real seductive.

Derek: OH GOD!
Lexie: Sorry.
Derek: Just... ah... Sorry. Sorry, we're sorry.
Meredith: Sorry!
Derek: Sorry, we'll clean the counter top.
Lexie: Ah, you didn't used to do this before and now it's kind of all the time. Everywhere and I just.
Derek: Well, you know, it's... we're married now and things have changed a little. But, ah, we're sorry about the counter top.
Lexie: Ah, so you guys are. You're really, that it? The post it? That's for real?
Derek: Yeah. That's for real.
(Der shuts the door and laughs)
Lexie: (disgusted) UGH!

Arizona: Oh, I have wine. White and Red, and I have cigarettes. Which is awful I know, but I only smoke on very rare, very occasionally. And, only when I know I'm gonna be in trouble. Like now.
Callie: It was inappropriate. Not to mention manipulative and stupid. You smoke?
Arizona: I know. Listen, I know you have every right to be mad at me but I ran out of options. So...
Callie: It's an expensive test, there was no indication to do it, there was a reason Webber turned you down.
Arizona: So you didn't do it?
Callie: Of course I did it Arizona.
Arizona: Thank you!

Grey's Anatomy Season 6 Quotes

In medical school, we have a hundred lessons that teach us how to fight off death, and not one lesson on how to go on living.

Meredith (narrating)

According to Elisabeth Kubler-Ross, when we're dying or have suffered a catastrophic loss, we all move through five distinct stages of grief. We go into denial because the loss is so unthinkable we can't imagine it's true. We become angry with everyone, angry with survivors, angry with ourselves. Then we bargain. We beg. We plead. We offer everything we have, we offer our souls in exchange for just one more day. When the bargaining has failed and the anger is too hard to maintain, we fall into depression, despair, until finally we have to accept that we've done everything we can. We let go. We let go and move into acceptance.

Meredith (narrating)