[Sheldon karate chops Leonard in the shoulder]
Leonard: Ow! Why did you do that?
Sheldon: To send a message: she's not for you!
Leonard: What?
Sheldon: Not for you!

Let me know when you're done canoodling! Mommy needs a foot rub!

Mrs. Wolowitz

Amy: If it makes you feel any better, the only person who signed my yearbook was my mother.
Leonard: Aww.
Amy: "Dear, Amy. Self-respect and a hymen are better than friends and fun. Love, Mom."

Howard: Can you believe grown men sit around and play with toy trains?
Bernadette: That's pretty big talk for a man with a closet full of magic tricks at his mother's house.

Amy: Should I go? I've been told, sometimes, I overstay my welcome.
Leonard: Wha ... who told you that?
Amy: Well, most recently my gynecologist.

Howard: This may be hard for you to hear, but when I say "honey," I mean my fiancee.
Raj [whispers into Howard's ear]
Howard: Yeah, well, now it means her.

The tinier the train the more concentrated the fun.

Sheldon

Bernadette: I'm not going to live with your mother. Not now. Not ever.
Howard: Somebody, obviously, has some mommy issues.

I've seen pictures of your mother. Keep eating.

Sheldon [to Penny]

The Big Bang Theory Season 5 Episode 3 Quotes

Bernadette: I'm not going to live with your mother. Not now. Not ever.
Howard: Somebody, obviously, has some mommy issues.

I've seen pictures of your mother. Keep eating.

Sheldon [to Penny]