Wolowitz: He got bit by a radioactive rat.
Raj: Did he get superpowers?
Wolotiz: No, he got five stitches and a tetanus shot.

Penny: He wasn't intellectually stimulating enough.
Bernadette: Couldn't you just fool around with him and then listen to NPR?
Penny: Wouldn't help. Zack couldn't even spell NPR.

You actually want to deceive your father with some sort of sham, playacting and kissing? Because I'm good with that.

Leonard

I want grandkids before I die and I want them to grow up in a house without wheels.

Wyatt

Bernadette: So we just sit here and stare at a screen and wait for something to happen?
Wolowitz: I did it with you when we watched The Notebook.

I'd like to say I'm very happy that you're back together, and if I can figure out a way to do so and sound sincere, I will.

Sheldon

Wolowitz: What kind of spaceship has a hole in the middle?
Raj: A Romulan battle bagel?

I was working with penicillin-resistant gonnorhea in the lab today, and I was just trying to remember if I washed my hands.

Bernadette

Indian Monopoly is just like regular Monopoly, but instead of money you use rupees, instead of building hotels you build call centers, and when you pick a chance card there's a chance you die of dysentery. And just FYI, that was racist.

Wolowitz

I'm not sure how this is scored, but I believe we may have won.

Amy

The Internet suggests that slumber party guests often engage in harmless experimentation with lesbianism.

Amy

I believe I'll gain acceptance by arbitrarily siding with your friends from time to time.

Amy

The Big Bang Theory Season 4 Quotes

You have broad hips and a certain corn-fed vigor. Is your womb available for rental?

Sheldon

At best, it's a modest leap forward from the technology that gave us Country Bear Jamboree.

Sheldon