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Tony's crew gets upset when Junior starts taxing long-time members so Tony brings in Johnny Sack from New York; Carmela is upset when Tony's medication renders him impotent.
Tony takes Meadow on a college tour through Maine where he discovers an ex-mobster who relocated there under witness protection; Father Phil comes to visit Carmela.
When Jackie Aprile dies of cancer, Tony and his crew agree to give in to Uncle Junior; Christopher gets angry when he discovers what happened to Brendan.
Tony, Paulie and Silvio enter into a business partnership with a Jewish hotel owner; Tony struggles with the terminal illness of his friend Jackie Aprile.
Christopher and Brandon do a little truck hijacking on their own, upsetting Uncle Junior; Tony's crew does a favor for AJ's teacher; Tony puts Livia in a home against her will.
Tony, the Capo in a Jersey mafia, begins seeing a therapist, Dr. Melfi after suffering from panic attacks.