Pike has appeared in numerous TV series in the UK. She made her film debut in the James Bond film, Die Another Day (2002). She then went on to star in many independent films, including Pride & Prejudice (2005), where she played Jane Bennett, Wrath of the Titans (2012), and opposite Tom Cruise in Jack Reacher (2012).
Pike received an Academy Award nomination for Best Actress for her role in Gone Girl (2012).
Rosamund currently portrays Moiraine Damodred in the Prime Video series The Wheel of Time.