Patrick Dempsey Happy For Katherine Heigl

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Friends are no substitute for family for Patrick Dempsey.

The actor declined his invitation to Grey's Anatomy co-star Katherine Heigl's wedding in favor of spending the holidays quietly with his family.

Katherine Heigl, 29, is set to marry singer Josh Kelley, 27, on December 23. Patrick won't be on hand, but he's thrilled for his co-star.

"I am so happy for her," he tells Entertainment Tonight. "I've never seen her so happy. He's a great guy, too, and they are a great couple."

The Family Man

Patrick Dempsey is looking forward to the role of dad this holiday season.

Patrick Dempsey, 41, who in addition to Grey's Anatomy is lighting up the big screen in this holiday season with Enchanted, will be spending the holidays with wife Jillian, daughter Tallulah, and 10-month-old twins Darby and Sullivan.

"It's the first Christmas with the boys. They'll be walking by then, so we're all very excited," Patrick Dempsey said.

Dempsey might be a no-show, but Grey's Anatomy will be represented at the wedding by castmate T.R. Knight, who will be a Heigl "bridesman."

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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I don't think that Katherine was planning on inviting all of the Grey's cast. Just the ones that she's closest to. In fact I am only seeing maybe a couple of the Grey's cast not getting an invite.

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Well of cos family will always come first and I am certainly not surprise that Patrick has declined the invitation. I think the only person Patrick will make extra effort, even if its on Christmas day to attend her wedding is Ellen Pompeo. I have a feeling he genuinely likes Ellen. However, that's only my opinion I maybe wrong.

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Grey's Anatomy Quotes

Amelia: I think I'm falling in love with Owen Hunt, and I'm really afraid that it's gonna destroy me.
Derek: It wouldn't be love if it didn't.

I want to marry you. I want to have kids with you. I want to build us a house. I want to settle down and grow old with you. I want to die when I'm 110 years old, in your arms. I don't want 48 uninterrupted hours. I want a lifetime. Mmm. Do you see what happens? I say things like that and you fight the urge to run in the opposite direction. It's okay, I understand. I didn't, but now I do, I do. You're just getting started and I've been doing this for a long time now. Deep down, you're still an intern, and you're not ready.

Derek