Grey's Anatomy News & Spoilers: Wednesday Edition

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Season Five of Grey's Anatomy is a little over one week (!) away and the rumors, spoilers and news - not to mention the excitement - surrounding the premiere, are building by the day. What's the latest on our favorite show this morning?

Enter Michael Ausiello of Entertainment Weekly ...

Q: Do you have any inside info on what Season 5 of Grey's Anatomy holds for Izzie and Alex? Their chemistry is great.

A: Let's just say you'll have a really good idea where these two are headed by the end of the two-hour opener on September 25 - which, BTW, I just watched and really enjoyed. Turns out Kevin McKidd is all that and a bag of chips.

Callica

Q: What's going on with Grey's Anatomy's Callica (Callie and Erica)?!

A: There's an awesome, awkward, totally endearing scene between the two of them at the end of the premiere. Sara Ramirez, in particular, is just fantastic. Meanwhile, looking ahead there's buzz that Callica may not be the only members of Seattle Grace's rapidly expanding LGBT community. There's a rumor going around that when the casting call for the new female intern went out last month, interested parties were told they had to be comfortable making out with both men and women. Coincidence then that the actress who got the role hails from The L Word? Only time will tell!

Q: How about some Grey's Anatomy scoop on someone other than Meredith Grey-Derek Shepherd or Cristina Yang-Owen Hunt?

A: The show is casting the role of a female patient who develops a multi-episode crush on one of the docs. My guess: We're looking at a potential love interest for McSteamy.

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Grey's Anatomy Quotes

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."