Is George really dead? Is Izzie leaving for five straight episodes or just an episode here and there? What do the looming layoffs at Seattle Grace mean for our residents?

Michael Ausiello of EW dishes on all of the above in his spoiler column today. Check out what he has to say about Grey's Anatomy and chime in with your comments ...

Q: I saw the first five minutes of the Grey’s Anatomy premiere on YouTube. Is there a chance George isn’t dead? Lexie seemed pretty convinced of this!

A: Yes, there’s a chance. A really, really small chance. Tiny. See where I’m going with this?

Q: So now that Katherine Heigl is adopting a child from Korea, does that re-explain producers’ decision to let her off the hook for five episodes of Grey’s Anatomy?

A: That’s not what I’m hearing. As I originally reported, all indications are that she’s taking off to make that Greg Berlanti movie. By the way, I’m now hearing that the five episodes Katherine will be missing may not be consecutive.

Q: Can I please have a Grey’s Anatomy scoop?

A: You may. The looming shakeup at Seattle Grace will have everyone fearing for his/her jobs. That includes Cristina, who is forced to consider the unthinkable: a career in pediatrics.

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.