Grey's Anatomy Without Patrick Dempsey: Would You Watch?

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The contracts of the original Grey's Anatomy cast will expire after the end of the upcoming eighth season, meaning May 2012 could be the end for them.

They could all sign new deals, of course, but Patrick Dempsey recently indicated that - at least as things stand at this moment - he's not inclined to.

"It will be my last," Dempsey said in an interview with Vogue. "I do not know what's going to happen to the other characters but for me it's done."

Making a Big Move

Dempsey's rep later clarified the quote, but you can't help but wonder what the future holds for him, and whether Derek is an irreplaceable character.

The show will likely go on regardless as long as the fan base remains loyal and delivers decent ratings. But will his departure hurt that very cause?

It certainly wouldn't be the same, but the show also has a ton of characters in what has become an enormous ensemble cast, so you never know.

Tell us: Would you watch Grey's Anatomy sans Patrick?

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Grey's Anatomy Quotes

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith

You think that true love is the only thing that can crush your heart; that will take your life and light it up or destroy it. Then you become a mother.

Meredith