Holley Fain Cast as McSteamy Love Interest on Grey's Anatomy

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Fans of Mark and Lexie may want to be sitting down before reading this.

Holley Fain, who once guest starred on Gossip Girl as the manipulative wife of Nate's cousin Trip, is coming to Grey's Anatomy this season - and she'll be romancing Mark Sloan.

She'll be a "recurring love interest" for McSteamy, according to TV Line.

Holley Fain Pic

Fain’s character, who debuts in mid-November, works as an ophthalmologist at another Seattle-area hospital. Her boss there will be played by Ernie Hudson of Ghostbusters fame.

She should certainly shake things up at SGMWH. In addition to Gossip Girl, Fain's credits also include stints on The Good Wife, Memphis Beat and Law & Order: Criminal Intent.

Are you excited Mark is potentially getting a girlfriend? Tell us in the comments below.

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Grey's Anatomy Quotes

[narrating] "At the end of the day, when it comes down to it, all we really want is to be close to somebody. So this thing where we all keep our distance and pretend not to care about each other, it's usually a load of bull. So we pick and choose who we want to remain close to, and once we've chosen those people, we tend to stick close by. No matter how much we hurt them. The people that are still with you at the end of the day, those are the ones worth keeping. And sure, sometimes close can be too close. But sometimes, that invasion of personal space, it can be exactly what you need."

MEREDITH

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)