Holley Fain Cast as McSteamy Love Interest on Grey's Anatomy

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Fans of Mark and Lexie may want to be sitting down before reading this.

Holley Fain, who once guest starred on Gossip Girl as the manipulative wife of Nate's cousin Trip, is coming to Grey's Anatomy this season - and she'll be romancing Mark Sloan.

She'll be a "recurring love interest" for McSteamy, according to TV Line.

Holley Fain Pic

Fain’s character, who debuts in mid-November, works as an ophthalmologist at another Seattle-area hospital. Her boss there will be played by Ernie Hudson of Ghostbusters fame.

She should certainly shake things up at SGMWH. In addition to Gossip Girl, Fain's credits also include stints on The Good Wife, Memphis Beat and Law & Order: Criminal Intent.

Are you excited Mark is potentially getting a girlfriend? Tell us in the comments below.

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.