James Remar Cast in Grey's Anatomy Mystery Role

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Sandra Oh is out. But a familiar face is in.

ABC sources confirm to TV Line that James Remar - best known as Dexter Morgan's father - will appear on multiple episodes of Grey's Anatomy Season 10. Details on the veteran actor's actual role are unclear, however, though he will debut early on this fall.

James Remar on Dexter

The action picks up again on Grey's Anatomy Thursday, September 26 with a two-hour premiere in which we'll learn the fate of Richard Webber.

Remar, meanwhile, has also appeared on episodes of such hits shows as Wilfred, The Vampire Diaries and Hawaii Five-0.

Matt Richenthal is the Editor in Chief of TV Fanatic. Follow him on Twitter and on Google+.

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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.