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Grey's Anatomy Sneak Peek: An Impossible Decision

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As teased in the official ABC promo for Grey's Anatomy Season 10 Episode 21, tonight's all-new episode of this hit drama will mark the beginning of the end for Cristina Yang.

Yes, fans, it's time to break out that box of Kleenex and prepare to say farewell.

What will drive Cristina away from Seattle?

That answer remains unclear, but the following sneak peek from "Change of Heart" may give us an idea of the sort of stress she will soon be under.

Check it out now and watch as Cristina offers parents of two kids an impossible decision, one they tell her she has to make:

Need to catch up on the series before Cristina says goodbye for good?

You can always watch Grey's Anatomy online via TV Fanatic. We make it easy.

Matt Richenthal is the Editor in Chief of TV Fanatic. Follow him on Twitter and on Google+.

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Did Yang ever figure out what was causing all of these kids to be sick? I remember she ruled out a virus and genetic. The last thing I remember, she was evaluating their house. We never got an answer though.....did we?