Remember Gizzie? As in George and Izzie? You can be forgiven if you don't, but here they are in a cute, recent photo.
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Is Izzie alright? When will her condition be revealed? Do viewers even care at this point? We will have to stay tuned to answer all of those.
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A picture of Alex and Izzie in "Beat Your Heart Out," from the fifth season of Grey's Anatomy. What does the future hold for them?
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Izzie and ghost Denny share a passionate embrace.
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Izzie and Denny have it out on Grey's Anatomy. He vanishes, possibly for good, shortly thereafter.
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Izzie Stevens definitely does. But when will we learn why?!
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Alex Karev is unmoved by Izzie's confessions of having sex with Denny.
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Sometimes you have to, if you're Izzie Stevens. Girl is nothing if not unconventional!
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Grey's Anatomy Quotes

[narrating] "At some point, you have to make a decision. Boundaries don't keep other people out, they fence you in. Life is messy, that's how we're made. So you can waste your life drawing lines or you can live your life crossing them. But there are some lines that are way too dangerous to cross. Here's what I know. If you're willing to throw caution to the wind and take a chance, the view from the other side... is spectacular."

MEREDITH

[narrating] The human life is made up of choices. Yes or no. In or out. Up or down. And then there are the choices that matter. Love or hate. To be a hero or to be a coward. To fight or to give in. To live. Or die. Live or die. That's the important choice. And it's not always in our hands.

Derek