It looks like that's about to happen in the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," which we see a scene from here.
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At least Izzie seems to be. In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," Dr. Stevens and other doctors at Seattle Grace stand outside. What will happen next?!
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," five of our favorite Seattle Grace staff members stand outside. Something tells us something bad is going to happen.
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," four of our favorite Seattle Grace staff members stand outside their place of employment.
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," Izzie helps a trauma patient out of the car. Looks intense!
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Don't count on it, according to some of the Grey's Anatomy spoilers we've read.
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In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Izzie is up in the face of Alex, ready to tell him how she feels. How will this end?
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In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Izzie is not about to take any more crap from Alex. This Rebecca stuff has gone on long enough.
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In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Izzie is not about to take crap from Alex. She's gonna stand up for what she wants.
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We do heart Izzie in spite of her flaws. Here she is in a photo from the fourth season finale of Grey's Anatomy, "Freedom."
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A photo from the fourth season finale of Grey's Anatomy, "Freedom." Alex Karev and Izzie Stevens are in the heat of a discussion... will the episode end with them getting back together?
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A photo from the fourth season finale of Grey's Anatomy, "Freedom." Alex Karev tends to Rebecca as Izzie Stevens looks on. What will happen between the two?
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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

Lexie: [narrating] Grief may be a thing we all have in common, but it looks different on everyone.
Mark: It isn't just death we have to grieve. It's life. It's loss. It's change.
Alex: And when we wonder why it has to suck so much sometimes, has to hurt so bad. The thing we gotta try to remember is that it can turn on a dime.
Izzie: That's how you stay alive. When it hurts so much you can't breathe, that's how you survive.
Derek: By remembering that one day, somehow, impossibly, you won't feel this way. It won't hurt this much.
Bailey: Grief comes in its own time for everyone, in its own way.
Owen: So the best we can do, the best anyone can do, is try for honesty.
Meredith: The really crappy thing, the very worst part of grief is that you can't control it.
Arizona: The best we can do is try to let ourselves feel it when it comes.
Callie: And let it go when we can.
Meredith: The very worst part is that the minute you think you're past it, it starts all over again.
Cristina: And always, every time, it takes your breath away.
Meredith: There are five stages of grief. They look different on all of us, but there are always five.
Alex: Denial.
Derek: Anger.
Bailey: Bargaining.
Lexie: Depression.
Richard: Acceptance.