Remember Gizzie? As in George and Izzie? You can be forgiven if you don't, but here they are in a cute, recent photo.
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Is Izzie alright? When will her condition be revealed? Do viewers even care at this point? We will have to stay tuned to answer all of those.
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A picture of Alex and Izzie in "Beat Your Heart Out," from the fifth season of Grey's Anatomy. What does the future hold for them?
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Izzie and ghost Denny share a passionate embrace.
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Izzie and Denny have it out on Grey's Anatomy. He vanishes, possibly for good, shortly thereafter.
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Izzie Stevens definitely does. But when will we learn why?!
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Alex Karev is unmoved by Izzie's confessions of having sex with Denny.
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Sometimes you have to, if you're Izzie Stevens. Girl is nothing if not unconventional!
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Izzie Stevens and Denny Duquette have been reunited (in one way or another) here in Season Five of Grey's Anatomy.
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Alex and Izzie appear to be getting closer in "These Ties That Bind," from the fifth season of Grey's Anatomy. But you know some problems are bound to come up anytime soon.
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We will have to see why, but in "These Ties That Bind," from the fifth season of Grey's Anatomy, Izzie sure looks happy about something!
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This photo shows a little PDA (emphasis on little) between Alex and Izzie in "These Ties That Bind," from the fifth season of Grey's Anatomy.
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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

Lexie: [narrating] Grief may be a thing we all have in common, but it looks different on everyone.
Mark: It isn't just death we have to grieve. It's life. It's loss. It's change.
Alex: And when we wonder why it has to suck so much sometimes, has to hurt so bad. The thing we gotta try to remember is that it can turn on a dime.
Izzie: That's how you stay alive. When it hurts so much you can't breathe, that's how you survive.
Derek: By remembering that one day, somehow, impossibly, you won't feel this way. It won't hurt this much.
Bailey: Grief comes in its own time for everyone, in its own way.
Owen: So the best we can do, the best anyone can do, is try for honesty.
Meredith: The really crappy thing, the very worst part of grief is that you can't control it.
Arizona: The best we can do is try to let ourselves feel it when it comes.
Callie: And let it go when we can.
Meredith: The very worst part is that the minute you think you're past it, it starts all over again.
Cristina: And always, every time, it takes your breath away.
Meredith: There are five stages of grief. They look different on all of us, but there are always five.
Alex: Denial.
Derek: Anger.
Bailey: Bargaining.
Lexie: Depression.
Richard: Acceptance.