Amy has a request of Sheldon on the episode "The Desperation Emanation." She wants to introduce him to her mother.
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That's Katee Sackhoff and that's George Takei. Both guest star as themselves on the episode "The Hot Troll Deviation."
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Who needs human companionship?!? Not Sheldon, this character hopes, on the episode titled "The Zazzy Substitution."
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How can Sheldon live longer? That's what he tries to figure out on the episode "The Cruciferous Vegetable Amplification."
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Say hello to Sheldon's nemesis on The Big Bang Theory: oh, yes, it's Evil Wil Wheaton!
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The Big Bang Theory airs on a new night during its fourth season. But this poster promises the same old hilarity.
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Sheldon requires a chaperon on his first date when season four of The Big Bang Theory kicks off. Penny is chosen for the job.
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Sheldon has a request for Penny on the fourth season premiere of The Big Bang Theory. Will she tag along on a date with him?
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TBBT Quotes

Penny: Hey, Sheldon, did you change your Wi-Fi password again?
Sheldon: Yes, it's "Penny, get your own Wi-Fi." No spaces.

Sheldon: Why do you have the Chinese character for "soup" tattooed on your right buttock?
Penny: It's not "soup," it's "courage."
Sheldon: No it isn't. But I suppose it does take courage to demonstrate that kind of commitment to soup.
Penny: How'd you see it? You said you wouldn't look.
Sheldon: Sorry. As I told you, the hero always peeks.