Sometimes, you need to drive an axe through the skull of a zombie. This typically ensures death.
Oops! Rick is on the run on The Walking Dead's second episode, as he accidentally causes a group of survivors to be trapped by the Walkers.

The Walking Dead Season 1 Episode 2 Quotes

Glenn: You're surrounded by "Walkers." That's the bad news.
Rick: There's good news?
Glenn: No.

Dale: If you see anything, holler. I'll come running.
Lori: Yes, mom.