Jane Kaczmarek guest stars on the Wilfred episode "Pride." She appears in this scene alongside Jason Gann and Elijah Wood.
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Wilfred and Ryan confer in this scene from the FX drama. The two of them have an odd relationship, as perhaps you can tell here.
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Wilfred finds a new friend on "Compassion." It's Ryan's mother, played by Mary Steenburgen.
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This is a typical interaction for Wilfred and Ryan. The latter is a bit freaked out by the former.
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Just a man and his dog? Not exactly. This is a photo fro "Isolation."
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Guess what? Ryan's mom is sort of crazy, too, as proven by this photo.
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Dwight Yoakam guest stars here on Wilfred. It's a scene from "Doubt."
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Jason Gann portrays the title character on Wilfred. He's a dog who looks like a human, to at least one person.
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Wilfred Quotes

Ryan: I thought it would make me sound Effete.
Wilfred: So does saying the word "effete."

Ryan: Get off.
Wilfred: I'm trying to!