Lisa Edelstein stars on House as the key character of Lisa Cuddy. She's one of our favorite actresses on TV. UPDATE: The actress exited House after season seven.
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Lisa Edelstein is perfect for the role of Lisa Cuddy. She's starred on House since its inception.
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House Quotes

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House

Masters: Why is your assumption of his guilt more valid than my assumption of his selflessness?
House: Because my assumption is baked up by millions of men, and Taub, who cheated on their wives.