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I'd kill my rabbi with a pork chop to be with your sister

Wolowitz: Okay forgot giant ants. How about giant rabbits?
Raj: Big or small, I don't like rabbits. They always look like they're about to say something, but they never do.
Sheldon: Rabbits do have a respiratory system that would support great size. And as a side note, they are one of the few animals whose scrotum is on the front of the penis.
Raj: Maybe that's what they want to talk about.

Raj: In Avatar, when they have sex on pandora they hook up their ponytails, so we know that their ponytails are like their junk.
Wolowitz: Yeah, so?
Raj: So when they ride horses and fly on the birds, they also use their ponytails...
Wolowitz: What's your point?
Raj: My point is if I were a horse or a bird, I'd be very nervous around James Cameron.

Howard: Tell her I'm really sorry. And if she doesn't want to marry me, I get it. But what I really want her to know is the guy that she is really disgusted by is the guy that I'm disgusted by, too. But, that guy doesn't exist anymore; he's gone. And the reason is because of her. So, if this relationship is over, let her know that she made me a better man, and tell her thank you.
Penny: Oh my god, Howard! That's the most beautiful thing I've ever heard. And it came out of you.

Mrs. Wolowitz: Howard, get the door!
Howard: Really, is that what you do when someone knocks? I had no idea

Wolowitz: You love that spot.
Sheldon: No, I love my mother. My feelings for my spot are much greater. It is the singular location in space around which revolves my entire universe. And now it's yours.

Wolowitz [about his phone call]: Looks like I'm going to have sex tonight
Penny: His right hand is calling him?

Wolowitz: Sheldon. You remember the first few weeks; we were looking for magnetic monopoles and not finding anything, and you were acting like an obnoxious, giant dictator?
Raj: I thought we were going to be gentle with him.
Wolowitz: That's why I added the "tator"

But if she dumps you, she'll have a new boyfriend by tomorrow morning, and you'll have a new girlfriend when you figure out how to build one.

Oh look! It's Leonard and R2-D-bag.

Raj: Come on, Sheldon, Star Wars.
Howard: I'm pushing play. I mean it. If we don't start soon, George Lucas is going to change it again.

Howard: No ... about my job. I want you to tell me I'm good at what I do.
Sheldon: You're obviously good at what you do.
Howard: Well, then why are you always ripping on me?
Sheldon: Oh, I understand the confusion. I have never said that you are not good at what you do, it's just that what you do is not worth doing.

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TBBT Quotes

Sheldon: I recently read that during World War Two, Joseph Stalin had a research program to create supersoldiers by having women impregnated by gorillas.
Howard: What a sick use of science.
Raj: Hey, as long as the baby's healthy.
Amy: I wonder if Stalin considered any other animals.
Leonard: Hippos are the deadliest creature. A half-human, half-hippo soldier would be pretty badass.
Howard: Yes, but when they're hungry-hungry, you can stop them with marbles.
Sheldon: Yeah, the correct animal for interspecies supersolider is koala. You would wind up with an army so cute it couldn't be attacked.

As soon as we get home, I want to have coitus with Amy. Okay, she can't hear.

Sheldon
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