May: Coulson has another way. But it's risky and irresponsible.
Mack: Then why are you smiling?

Mack: How's he holding up?
May: No one comes to me with their feelings.
Mack: Makes sense.

Daisy: Had to get the band back together. Anyone that can fly this thing?
Jemma: May, you can't even walk.
May: But I can still fly.

You're hurting my brain.

Jemma: I just feel guilty. All the time. How do you make it stop?
May: You don't. You use it, channel it.
Jemma: Is that what you're doing?

Lincoln, forget what I said! Rush in and use your powers!

May: We find the Strucker kid, he'll lead us back to Ward.
Bobbi: You got a how?
May: S.H.I.E.L.D's been monitoring several Hydra bank accounts for a while now, one just woke up. Cayman Islands.
Bobbi: Strucker needed funds, makes sense. So what's the op?
May: How's your Mandarin?
Bobbi: [In Mandarin] You tell me.
May: If we head down there, maybe we'll pick up his trail. He's on the run from Ward. From us. Almost makes me feel sorry for the kid.

Coulson: Since when did you become a high ranking member of team Gonzales?
May: Someone had to run the base while you were gone. Having a seat allowed me to keep you safe.
Coulson: I was fine on my own.
May: Seems that's how you operate best.
Coulson: What the hell is that supposed to mean.
May: That you've been lying to me. Every since S.H.I.E.L.D. fell, all those overseas trips you were taking. They were never about recruiting new agents were they? You want to tell me what Theta Protocol is?
Coulson: No.
May: Because you don't trust me.
Coulson: Because you're not the director of S.H.I.E.L.D.
May: Neither are you.

Dr. Garner: I haven't worked with S.H.I.E.L.D. in a long while. I moved on for a reason.
May: It's a different S.H.I.E.L.D., Coulson's the director now.
Dr. Garner: Okay, but why me? Is this Skye that bad?
May: She's that good; good agent.

Coulson: You agree with her. You think Skye is more than we can handle.
Agent May: Look, most of the time, I believe what I see, you know that but...
Coulson: But?
Agent May: You died. You were brought back, with a map to a city encoded in your DNA. Our team's first mission.
Coulson: We picked up Skye.
Agent May: Last week, we took her to that city. I can't help but remember what Lumley said. Wherever Skye goes...
Coulson: Death follows.

Vin-Tak: Asgardian, well that explains a lot.
Lady Sif: It is true, we do not trust Kree. That is why I am here. When Heimdall saw that one landed on your world, Odin charged me with retrieving him.
Vin-Tak: So you came to pick a fight.
Lady Sif: We know enough about Kree history to be concerned.
Vin-Tak: Well then if you know Kree history perhaps you've heard the tale of Terragenesis?
Lady Sif: Of course, ancient Kree descending on planets altering the inhabitants to fight their war.
Vin-Tak: And Earth was one of them.
Skye: Blue angels who fell from the sky.
Lady Sif: Eons ago the Kree waged a very long war. Casualties were high and they needed more soldiers.
Agent May: You mean cannon fodder.
Vin-Tak: We needed killers. One vicious faction among the Kree genetically modified other creatures' DNA. These modifications can be activated with Terrigen Crystals.
Lady Sif: We know these torturous experiments failed.
Vin-Tak: Not on Earth, here we had to shut them down. This faction had built a city. They brought with them the Diviners, which hold the crystals. Their plans were discovered and thwarted by the better of my kind. Putting an end to that dark chapter of our past.
Skye: Until now.

Agent May: What about Thor?
Lady Sif: I do not know this word, yet when you say it I want to smile.

Agents of S.H.I.E.L.D. Quotes

Fitz: Things are about to get complicated.
Simmons: You mean once we have sex?

Skye: Wow, look at them, the popular kids. Who knew?
Ward: I did.